node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR50022.1 | EAR50986.1 | OG2516_07465 | OG2516_03258 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.973 |
EAR50022.1 | EAR52299.1 | OG2516_07465 | OG2516_07477 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | 0.999 |
EAR50022.1 | EAR52414.1 | OG2516_07465 | OG2516_08052 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.986 |
EAR50022.1 | EAR52417.1 | OG2516_07465 | OG2516_08067 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.966 |
EAR50022.1 | EAR52418.1 | OG2516_07465 | OG2516_08072 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.570 |
EAR50022.1 | EAR52419.1 | OG2516_07465 | OG2516_08077 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.959 |
EAR50022.1 | EAR52675.1 | OG2516_07465 | OG2516_00574 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.966 |
EAR50022.1 | EAR52991.1 | OG2516_07465 | OG2516_11026 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG0029 Aspartate oxidase. | 0.966 |
EAR50022.1 | sucC | OG2516_07465 | OG2516_08127 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.951 |
EAR50022.1 | sucD | OG2516_07465 | OG2516_08137 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.965 |
EAR50986.1 | EAR50022.1 | OG2516_03258 | OG2516_07465 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.973 |
EAR50986.1 | EAR52299.1 | OG2516_03258 | OG2516_07477 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | 0.973 |
EAR50986.1 | EAR52414.1 | OG2516_03258 | OG2516_08052 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.990 |
EAR50986.1 | EAR52417.1 | OG2516_03258 | OG2516_08067 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.912 |
EAR50986.1 | EAR52419.1 | OG2516_03258 | OG2516_08077 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.877 |
EAR50986.1 | EAR52675.1 | OG2516_03258 | OG2516_00574 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.912 |
EAR50986.1 | EAR52991.1 | OG2516_03258 | OG2516_11026 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0029 Aspartate oxidase. | 0.912 |
EAR50986.1 | sucC | OG2516_03258 | OG2516_08127 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.986 |
EAR50986.1 | sucD | OG2516_03258 | OG2516_08137 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.963 |
EAR52299.1 | EAR50022.1 | OG2516_07477 | OG2516_07465 | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.999 |