node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR49912.1 | EAR52418.1 | OG2516_16796 | OG2516_08072 | Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.868 |
EAR52414.1 | EAR52417.1 | OG2516_08052 | OG2516_08067 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |
EAR52414.1 | EAR52418.1 | OG2516_08052 | OG2516_08072 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.999 |
EAR52414.1 | EAR52419.1 | OG2516_08052 | OG2516_08077 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.999 |
EAR52414.1 | EAR52432.1 | OG2516_08052 | OG2516_08142 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.945 |
EAR52414.1 | EAR52675.1 | OG2516_08052 | OG2516_00574 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.998 |
EAR52414.1 | EAR52991.1 | OG2516_08052 | OG2516_11026 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG0029 Aspartate oxidase. | 0.997 |
EAR52414.1 | fumC | OG2516_08052 | OG2516_06077 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.974 |
EAR52414.1 | sucC | OG2516_08052 | OG2516_08127 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.991 |
EAR52414.1 | sucD | OG2516_08052 | OG2516_08137 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.994 |
EAR52417.1 | EAR52414.1 | OG2516_08067 | OG2516_08052 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
EAR52417.1 | EAR52418.1 | OG2516_08067 | OG2516_08072 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.999 |
EAR52417.1 | EAR52419.1 | OG2516_08067 | OG2516_08077 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.999 |
EAR52417.1 | EAR52432.1 | OG2516_08067 | OG2516_08142 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.935 |
EAR52417.1 | fumC | OG2516_08067 | OG2516_06077 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.996 |
EAR52417.1 | sucC | OG2516_08067 | OG2516_08127 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.983 |
EAR52417.1 | sucD | OG2516_08067 | OG2516_08137 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.988 |
EAR52418.1 | EAR49912.1 | OG2516_08072 | OG2516_16796 | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | 0.868 |
EAR52418.1 | EAR52414.1 | OG2516_08072 | OG2516_08052 | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
EAR52418.1 | EAR52417.1 | OG2516_08072 | OG2516_08067 | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |