node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR49590.1 | EAR49809.1 | OG2516_09138 | OG2516_08643 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.919 |
EAR49590.1 | EAR52359.1 | OG2516_09138 | OG2516_07777 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase. | 0.974 |
EAR49590.1 | EAR52947.1 | OG2516_09138 | OG2516_10806 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.955 |
EAR49590.1 | EAR52955.1 | OG2516_09138 | OG2516_10846 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases. | 0.986 |
EAR49590.1 | cobB | OG2516_09138 | OG2516_03595 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.958 |
EAR49590.1 | cobD | OG2516_09138 | OG2516_10811 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.976 |
EAR49590.1 | cobQ | OG2516_09138 | OG2516_04788 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.992 |
EAR49590.1 | cobS | OG2516_09138 | OG2516_15724 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Putative Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.972 |
EAR49807.1 | EAR49808.1 | OG2516_08633 | OG2516_08638 | Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Hypothetical protein. | 0.746 |
EAR49807.1 | EAR49809.1 | OG2516_08633 | OG2516_08643 | Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.746 |
EAR49808.1 | EAR49807.1 | OG2516_08638 | OG2516_08633 | Hypothetical protein. | Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.746 |
EAR49808.1 | EAR49809.1 | OG2516_08638 | OG2516_08643 | Hypothetical protein. | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.856 |
EAR49809.1 | EAR49590.1 | OG2516_08643 | OG2516_09138 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.919 |
EAR49809.1 | EAR49807.1 | OG2516_08643 | OG2516_08633 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.746 |
EAR49809.1 | EAR49808.1 | OG2516_08643 | OG2516_08638 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | Hypothetical protein. | 0.856 |
EAR49809.1 | EAR52359.1 | OG2516_08643 | OG2516_07777 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase. | 0.888 |
EAR49809.1 | EAR52947.1 | OG2516_08643 | OG2516_10806 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.878 |
EAR49809.1 | EAR52955.1 | OG2516_08643 | OG2516_10846 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases. | 0.887 |
EAR49809.1 | cobB | OG2516_08643 | OG2516_03595 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.879 |
EAR49809.1 | cobD | OG2516_08643 | OG2516_10811 | ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.879 |