| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49740.1 | EAR49741.1 | OG2516_08743 | OG2516_08748 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.896 |
| EAR49740.1 | EAR49742.1 | OG2516_08743 | OG2516_08753 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | COG3119 Arylsulfatase A and related enzymes. | 0.775 |
| EAR49740.1 | EAR50986.1 | OG2516_08743 | OG2516_03258 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.762 |
| EAR49740.1 | EAR52866.1 | OG2516_08743 | OG2516_10401 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.450 |
| EAR49740.1 | betI | OG2516_08743 | OG2516_08758 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Transcriptional regulator, BetI; Repressor involved in choline regulation of the bet genes. | 0.927 |
| EAR49741.1 | EAR49740.1 | OG2516_08748 | OG2516_08743 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.896 |
| EAR49741.1 | EAR49742.1 | OG2516_08748 | OG2516_08753 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | COG3119 Arylsulfatase A and related enzymes. | 0.793 |
| EAR49741.1 | EAR50080.1 | OG2516_08748 | OG2516_06404 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.828 |
| EAR49741.1 | EAR50986.1 | OG2516_08748 | OG2516_03258 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.768 |
| EAR49741.1 | EAR51176.1 | OG2516_08748 | OG2516_14915 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.763 |
| EAR49741.1 | EAR52866.1 | OG2516_08748 | OG2516_10401 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.910 |
| EAR49741.1 | EAR53058.1 | OG2516_08748 | OG2516_11361 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.757 |
| EAR49741.1 | betI | OG2516_08748 | OG2516_08758 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Transcriptional regulator, BetI; Repressor involved in choline regulation of the bet genes. | 0.858 |
| EAR49741.1 | fmt | OG2516_08748 | OG2516_09073 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.901 |
| EAR49741.1 | pckA | OG2516_08748 | OG2516_08708 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.758 |
| EAR49742.1 | EAR49740.1 | OG2516_08753 | OG2516_08743 | COG3119 Arylsulfatase A and related enzymes. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.775 |
| EAR49742.1 | EAR49741.1 | OG2516_08753 | OG2516_08748 | COG3119 Arylsulfatase A and related enzymes. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.793 |
| EAR49742.1 | betI | OG2516_08753 | OG2516_08758 | COG3119 Arylsulfatase A and related enzymes. | Transcriptional regulator, BetI; Repressor involved in choline regulation of the bet genes. | 0.855 |
| EAR50080.1 | EAR49741.1 | OG2516_06404 | OG2516_08748 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.828 |
| EAR50080.1 | EAR50986.1 | OG2516_06404 | OG2516_03258 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.860 |