Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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EAR50511.1Nitroreductase family protein; COG0778 Nitroreductase. (229 aa)    
Predicted Functional Partners:
EAR50512.1
malonyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
   
   0.908
EAR52793.1
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.869
EAR51459.1
Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family.
    
 0.837
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.773
EAR50338.1
COG0842 ABC-type multidrug transport system, permease component.
  
    0.761
EAR51496.1
COG0842 ABC-type multidrug transport system, permease component.
  
    0.761
ubiX
3-polyprenyl-4-hydroxybenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
     
  0.705
EAR50508.1
COG1904 Glucuronate isomerase.
     
 0.696
EAR49806.1
Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases.
  
    0.688
EAR50509.1
D-mannonate oxidoreductase; COG0246 Mannitol-1-phosphate/altronate dehydrogenases.
       0.686
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
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