| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50287.1 | guaA | OG2516_14713 | OG2516_02504 | COG0060 Isoleucyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.753 |
| EAR50287.1 | ileS | OG2516_14713 | OG2516_14708 | COG0060 Isoleucyl-tRNA synthetase. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.966 |
| EAR50287.1 | leuS | OG2516_14713 | OG2516_11966 | COG0060 Isoleucyl-tRNA synthetase. | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.973 |
| EAR50287.1 | metG | OG2516_14713 | OG2516_06347 | COG0060 Isoleucyl-tRNA synthetase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.978 |
| EAR50287.1 | pheS | OG2516_14713 | OG2516_10351 | COG0060 Isoleucyl-tRNA synthetase. | COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.513 |
| EAR50287.1 | pheT | OG2516_14713 | OG2516_09914 | COG0060 Isoleucyl-tRNA synthetase. | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.961 |
| EAR50287.1 | rpsS | OG2516_14713 | OG2516_08466 | COG0060 Isoleucyl-tRNA synthetase. | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.414 |
| guaA | EAR50287.1 | OG2516_02504 | OG2516_14713 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0060 Isoleucyl-tRNA synthetase. | 0.753 |
| guaA | ileS | OG2516_02504 | OG2516_14708 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.753 |
| guaA | leuS | OG2516_02504 | OG2516_11966 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.585 |
| guaA | metG | OG2516_02504 | OG2516_06347 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.703 |
| guaA | pheS | OG2516_02504 | OG2516_10351 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.594 |
| guaA | pheT | OG2516_02504 | OG2516_09914 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.958 |
| guaA | rplD | OG2516_02504 | OG2516_08481 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.735 |
| guaA | rpsB | OG2516_02504 | OG2516_02164 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.740 |
| guaA | rpsC | OG2516_02504 | OG2516_08456 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.920 |
| guaA | rpsS | OG2516_02504 | OG2516_08466 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.856 |
| ileS | EAR50287.1 | OG2516_14708 | OG2516_14713 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | COG0060 Isoleucyl-tRNA synthetase. | 0.966 |
| ileS | guaA | OG2516_14708 | OG2516_02504 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.753 |
| ileS | leuS | OG2516_14708 | OG2516_11966 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.976 |