Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAR52980.1Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal; COG3452 Predicted periplasmic ligand-binding sensor domain. (691 aa)    
Predicted Functional Partners:
EAR50848.1
PAS; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
 
 0.993
EAR51560.1
Two-component sensor histidine kinase; COG2203 FOG: GAF domain.
 0.992
EAR50849.1
COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 0.991
EAR51016.1
PAS sensor Signal Tranduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
   
 0.983
EAR49853.1
Signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain.
 
 0.978
EAR52372.1
Nineteen domain light and oxygen sensing his kinase; COG0642 Signal transduction histidine kinase.
 
0.958
EAR51152.1
Hypothetical protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 0.951
EAR52968.1
Sensor histidine kinase; COG2203 FOG: GAF domain.
 
  0.937
EAR52374.1
COG0642 Signal transduction histidine kinase.
 
 
0.922
EAR50327.1
Hypothetical protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  0.913
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
Server load: low (40%) [HD]