| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49780.1 | EAR52623.1 | OG2516_04763 | OG2516_05928 | Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation. | DnaJ domain protein; COG2214 DnaJ-class molecular chaperone. | 0.582 |
| EAR49780.1 | dnaJ | OG2516_04763 | OG2516_11106 | Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.495 |
| EAR49780.1 | dnaK | OG2516_04763 | OG2516_11101 | Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation. | Heat shock protein (Hsp70, DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.987 |
| EAR51247.1 | EAR51500.1 | OG2516_14571 | OG2516_17306 | Hypothetical protein; COG0457 FOG: TPR repeat. | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.538 |
| EAR51247.1 | EAR52623.1 | OG2516_14571 | OG2516_05928 | Hypothetical protein; COG0457 FOG: TPR repeat. | DnaJ domain protein; COG2214 DnaJ-class molecular chaperone. | 0.986 |
| EAR51247.1 | clpB | OG2516_14571 | OG2516_12576 | Hypothetical protein; COG0457 FOG: TPR repeat. | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.538 |
| EAR51247.1 | dnaJ | OG2516_14571 | OG2516_11106 | Hypothetical protein; COG0457 FOG: TPR repeat. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.986 |
| EAR51247.1 | dnaK | OG2516_14571 | OG2516_11101 | Hypothetical protein; COG0457 FOG: TPR repeat. | Heat shock protein (Hsp70, DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.971 |
| EAR51247.1 | groEL | OG2516_14571 | OG2516_17146 | Hypothetical protein; COG0457 FOG: TPR repeat. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.578 |
| EAR51247.1 | grpE | OG2516_14571 | OG2516_11351 | Hypothetical protein; COG0457 FOG: TPR repeat. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.409 |
| EAR51500.1 | EAR51247.1 | OG2516_17306 | OG2516_14571 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Hypothetical protein; COG0457 FOG: TPR repeat. | 0.538 |
| EAR51500.1 | EAR52623.1 | OG2516_17306 | OG2516_05928 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | DnaJ domain protein; COG2214 DnaJ-class molecular chaperone. | 0.914 |
| EAR51500.1 | dnaJ | OG2516_17306 | OG2516_11106 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.918 |
| EAR51500.1 | dnaK | OG2516_17306 | OG2516_11101 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein (Hsp70, DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.991 |
| EAR51500.1 | groEL | OG2516_17306 | OG2516_17146 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.825 |
| EAR51500.1 | groS | OG2516_17306 | OG2516_17151 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10 (GroES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.836 |
| EAR51500.1 | grpE | OG2516_17306 | OG2516_11351 | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.917 |
| EAR52623.1 | EAR49780.1 | OG2516_05928 | OG2516_04763 | DnaJ domain protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation. | 0.582 |
| EAR52623.1 | EAR51247.1 | OG2516_05928 | OG2516_14571 | DnaJ domain protein; COG2214 DnaJ-class molecular chaperone. | Hypothetical protein; COG0457 FOG: TPR repeat. | 0.986 |
| EAR52623.1 | EAR51500.1 | OG2516_05928 | OG2516_17306 | DnaJ domain protein; COG2214 DnaJ-class molecular chaperone. | ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.914 |
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