| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50022.1 | EAR52299.1 | OG2516_07465 | OG2516_07477 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | 0.999 |
| EAR50022.1 | dnaJ | OG2516_07465 | OG2516_11106 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.970 |
| EAR50022.1 | groEL | OG2516_07465 | OG2516_17146 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.443 |
| EAR51247.1 | EAR52606.1 | OG2516_14571 | OG2516_05843 | Hypothetical protein; COG0457 FOG: TPR repeat. | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 0.971 |
| EAR51247.1 | dnaJ | OG2516_14571 | OG2516_11106 | Hypothetical protein; COG0457 FOG: TPR repeat. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.986 |
| EAR51247.1 | dnaK | OG2516_14571 | OG2516_11101 | Hypothetical protein; COG0457 FOG: TPR repeat. | Heat shock protein (Hsp70, DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.971 |
| EAR51247.1 | groEL | OG2516_14571 | OG2516_17146 | Hypothetical protein; COG0457 FOG: TPR repeat. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.578 |
| EAR51247.1 | grpE | OG2516_14571 | OG2516_11351 | Hypothetical protein; COG0457 FOG: TPR repeat. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.409 |
| EAR52299.1 | EAR50022.1 | OG2516_07477 | OG2516_07465 | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.999 |
| EAR52299.1 | dnaJ | OG2516_07477 | OG2516_11106 | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.970 |
| EAR52299.1 | groEL | OG2516_07477 | OG2516_17146 | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.443 |
| EAR52606.1 | EAR51247.1 | OG2516_05843 | OG2516_14571 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Hypothetical protein; COG0457 FOG: TPR repeat. | 0.971 |
| EAR52606.1 | dnaJ | OG2516_05843 | OG2516_11106 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.997 |
| EAR52606.1 | groEL | OG2516_05843 | OG2516_17146 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.974 |
| EAR52606.1 | grpE | OG2516_05843 | OG2516_11351 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.993 |
| EAR52606.1 | rpsE | OG2516_05843 | OG2516_08396 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.792 |
| EAR52606.1 | rpsG | OG2516_05843 | OG2516_08511 | Heat shock protein, Hsp70 family protein; COG0443 Molecular chaperone. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.739 |
| dnaJ | EAR50022.1 | OG2516_11106 | OG2516_07465 | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.970 |
| dnaJ | EAR51247.1 | OG2516_11106 | OG2516_14571 | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Hypothetical protein; COG0457 FOG: TPR repeat. | 0.986 |
| dnaJ | EAR52299.1 | OG2516_11106 | OG2516_07477 | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Formate dehydrogenase, beta subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit. | 0.970 |
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