| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR51594.1 | EAR53020.1 | OG2516_01706 | OG2516_11171 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Hypothetical protein; COG0802 Predicted ATPase or kinase. | 0.804 |
| EAR51594.1 | nnrD | OG2516_01706 | OG2516_02334 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.429 |
| EAR52398.1 | EAR53020.1 | OG2516_07972 | OG2516_11171 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Hypothetical protein; COG0802 Predicted ATPase or kinase. | 0.994 |
| EAR52398.1 | nnrD | OG2516_07972 | OG2516_02334 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.412 |
| EAR52398.1 | tsaD | OG2516_07972 | OG2516_11656 | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Glycoprotease (M22) metalloprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.995 |
| EAR53019.1 | EAR53020.1 | OG2516_11166 | OG2516_11171 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | Hypothetical protein; COG0802 Predicted ATPase or kinase. | 0.772 |
| EAR53019.1 | EAR53021.1 | OG2516_11166 | OG2516_11176 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | Hypothetical protein; COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | 0.772 |
| EAR53019.1 | EAR53022.1 | OG2516_11166 | OG2516_11181 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). | 0.772 |
| EAR53019.1 | EAR53023.1 | OG2516_11166 | OG2516_11186 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | Putative Helicase/Exonuclease; COG3893 Inactivated superfamily I helicase. | 0.910 |
| EAR53019.1 | EAR53024.1 | OG2516_11166 | OG2516_11191 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | ATP-dependent DNA helicase, UvrD/Rep family protein; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily. | 0.772 |
| EAR53019.1 | EAR53025.1 | OG2516_11166 | OG2516_11196 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.695 |
| EAR53020.1 | EAR51594.1 | OG2516_11171 | OG2516_01706 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.804 |
| EAR53020.1 | EAR52398.1 | OG2516_11171 | OG2516_07972 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.994 |
| EAR53020.1 | EAR53019.1 | OG2516_11171 | OG2516_11166 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Hypothetical protein; COG2202 FOG: PAS/PAC domain. | 0.772 |
| EAR53020.1 | EAR53021.1 | OG2516_11171 | OG2516_11176 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Hypothetical protein; COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | 0.984 |
| EAR53020.1 | EAR53022.1 | OG2516_11171 | OG2516_11181 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). | 0.962 |
| EAR53020.1 | EAR53023.1 | OG2516_11171 | OG2516_11186 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Putative Helicase/Exonuclease; COG3893 Inactivated superfamily I helicase. | 0.916 |
| EAR53020.1 | EAR53024.1 | OG2516_11171 | OG2516_11191 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | ATP-dependent DNA helicase, UvrD/Rep family protein; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily. | 0.877 |
| EAR53020.1 | EAR53025.1 | OG2516_11171 | OG2516_11196 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.741 |
| EAR53020.1 | nnrD | OG2516_11171 | OG2516_02334 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.867 |