node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR50551.1 | EAR50679.1 | OG2516_04406 | OG2516_06267 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.867 |
EAR50551.1 | EAR50689.1 | OG2516_04406 | OG2516_06317 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG0460 Homoserine dehydrogenase. | 0.407 |
EAR50551.1 | EAR50777.1 | OG2516_04406 | OG2516_09268 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Aminotransferase class IV, putative D-alanine aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.954 |
EAR50551.1 | EAR50986.1 | OG2516_04406 | OG2516_03258 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.902 |
EAR50551.1 | EAR52442.1 | OG2516_04406 | OG2516_08192 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Putative dihydroxy-acid dehydratase protein; COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.957 |
EAR50551.1 | EAR53061.1 | OG2516_04406 | OG2516_11376 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.964 |
EAR50551.1 | ilvD | OG2516_04406 | OG2516_12311 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.954 |
EAR50551.1 | leuA | OG2516_04406 | OG2516_13364 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.880 |
EAR50551.1 | mdh | OG2516_04406 | OG2516_08112 | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.873 |
EAR50679.1 | EAR50551.1 | OG2516_06267 | OG2516_04406 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.867 |
EAR50679.1 | EAR50777.1 | OG2516_06267 | OG2516_09268 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Aminotransferase class IV, putative D-alanine aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.464 |
EAR50679.1 | EAR50986.1 | OG2516_06267 | OG2516_03258 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.988 |
EAR50679.1 | EAR52442.1 | OG2516_06267 | OG2516_08192 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Putative dihydroxy-acid dehydratase protein; COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.802 |
EAR50679.1 | EAR53061.1 | OG2516_06267 | OG2516_11376 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.877 |
EAR50679.1 | ilvD | OG2516_06267 | OG2516_12311 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.802 |
EAR50679.1 | leuA | OG2516_06267 | OG2516_13364 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.867 |
EAR50679.1 | mdh | OG2516_06267 | OG2516_08112 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.911 |
EAR50689.1 | EAR50551.1 | OG2516_06317 | OG2516_04406 | COG0460 Homoserine dehydrogenase. | 2-isopropylmalate synthase/homocitrate synthase family protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.407 |
EAR50689.1 | EAR50777.1 | OG2516_06317 | OG2516_09268 | COG0460 Homoserine dehydrogenase. | Aminotransferase class IV, putative D-alanine aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.873 |
EAR50689.1 | EAR50986.1 | OG2516_06317 | OG2516_03258 | COG0460 Homoserine dehydrogenase. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.563 |