| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR50569.1 | EAR50673.1 | OG2516_04496 | OG2516_06237 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.988 |
| EAR50569.1 | EAR50674.1 | OG2516_04496 | OG2516_06242 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.996 |
| EAR50569.1 | EAR50947.1 | OG2516_04496 | OG2516_13781 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.962 |
| EAR50569.1 | EAR51968.1 | OG2516_04496 | OG2516_13124 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.674 |
| EAR50569.1 | EAR51969.1 | OG2516_04496 | OG2516_13129 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG4311 Sarcosine oxidase delta subunit. | 0.986 |
| EAR50569.1 | EAR51970.1 | OG2516_04496 | OG2516_13134 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.986 |
| EAR50569.1 | EAR51971.1 | OG2516_04496 | OG2516_13139 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG4583 Sarcosine oxidase gamma subunit. | 0.984 |
| EAR50569.1 | EAR52291.1 | OG2516_04496 | OG2516_02604 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Putative sarcosine oxidase, alpha subunit; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.987 |
| EAR50569.1 | EAR52292.1 | OG2516_04496 | OG2516_02609 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.987 |
| EAR50569.1 | glyA | OG2516_04496 | OG2516_13144 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.822 |
| EAR50673.1 | EAR50569.1 | OG2516_06237 | OG2516_04496 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.988 |
| EAR50673.1 | EAR50674.1 | OG2516_06237 | OG2516_06242 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.999 |
| EAR50673.1 | EAR50947.1 | OG2516_06237 | OG2516_13781 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.987 |
| EAR50673.1 | EAR51968.1 | OG2516_06237 | OG2516_13124 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.989 |
| EAR50673.1 | EAR51969.1 | OG2516_06237 | OG2516_13129 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; COG4311 Sarcosine oxidase delta subunit. | 0.999 |
| EAR50673.1 | EAR51970.1 | OG2516_06237 | OG2516_13134 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.626 |
| EAR50673.1 | EAR51971.1 | OG2516_06237 | OG2516_13139 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; COG4583 Sarcosine oxidase gamma subunit. | 0.994 |
| EAR50673.1 | EAR52291.1 | OG2516_06237 | OG2516_02604 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Putative sarcosine oxidase, alpha subunit; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.623 |
| EAR50673.1 | EAR52292.1 | OG2516_06237 | OG2516_02609 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.997 |
| EAR50673.1 | glyA | OG2516_06237 | OG2516_13144 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.886 |