| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAR49723.1 | panC | OG2516_15919 | OG2516_13776 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.772 |
| EAR50332.1 | panC | OG2516_07293 | OG2516_13776 | Beta alanine-pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.772 |
| EAR50432.1 | panC | OG2516_08843 | OG2516_13776 | Ser/Thr protein phosphatase/nucleotidase, putative; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.792 |
| EAR50767.1 | panC | OG2516_09218 | OG2516_13776 | Aminotransferase, class III; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.772 |
| EAR50931.1 | EAR52508.1 | OG2516_13701 | OG2516_05353 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; COG1072 Panthothenate kinase. | 0.885 |
| EAR50931.1 | EAR52665.1 | OG2516_13701 | OG2516_00524 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 0.402 |
| EAR50931.1 | cmk | OG2516_13701 | OG2516_16996 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | COG0283 Cytidylate kinase. | 0.630 |
| EAR50931.1 | coaX | OG2516_13701 | OG2516_02838 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.891 |
| EAR50931.1 | panB | OG2516_13701 | OG2516_13771 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.541 |
| EAR50931.1 | panC | OG2516_13701 | OG2516_13776 | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.924 |
| EAR52508.1 | EAR50931.1 | OG2516_05353 | OG2516_13701 | Hypothetical protein; COG1072 Panthothenate kinase. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.885 |
| EAR52508.1 | coaX | OG2516_05353 | OG2516_02838 | Hypothetical protein; COG1072 Panthothenate kinase. | Transcriptional activator, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.492 |
| EAR52508.1 | panC | OG2516_05353 | OG2516_13776 | Hypothetical protein; COG1072 Panthothenate kinase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.863 |
| EAR52665.1 | EAR50931.1 | OG2516_00524 | OG2516_13701 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.402 |
| EAR52665.1 | panB | OG2516_00524 | OG2516_13771 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.954 |
| EAR52665.1 | panC | OG2516_00524 | OG2516_13776 | 2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.954 |
| cmk | EAR50931.1 | OG2516_16996 | OG2516_13701 | COG0283 Cytidylate kinase. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.630 |
| cmk | coaX | OG2516_16996 | OG2516_02838 | COG0283 Cytidylate kinase. | Transcriptional activator, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.531 |
| cmk | panC | OG2516_16996 | OG2516_13776 | COG0283 Cytidylate kinase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.926 |
| coaX | EAR50931.1 | OG2516_02838 | OG2516_13701 | Transcriptional activator, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.891 |