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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
ku-2Putative ATP-dependent DNA ligase protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (301 aa)    
Predicted Functional Partners:
EAR51244.1
Hypothetical protein; COG1793 ATP-dependent DNA ligase.
 
  
 0.986
EAR51245.1
Hypothetical protein; COG1793 ATP-dependent DNA ligase.
 
  
 0.986
EAR50857.1
Hypothetical protein; COG1793 ATP-dependent DNA ligase.
 
  
 0.951
EAR51248.1
Hypothetical protein; COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold.
 
     0.822
EAR51247.1
Hypothetical protein; COG0457 FOG: TPR repeat.
 
     0.805
EAR51249.1
COG0708 Exonuclease III.
       0.773
EAR51584.1
Hypothetical protein.
 
     0.538
EAR52914.1
Putative DNA topoisomerase I protein; COG3569 Topoisomerase IB.
 
    0.537
EAR51243.1
Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolaseoxidoreductase protein; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
       0.487
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
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