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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR49628.1DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. (356 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.965
EAR53077.1
Competence protein F; COG1040 Predicted amidophosphoribosyltransferases.
 
 
 0.944
EAR52362.1
Competence protein ComM; COG0606 Predicted ATPase with chaperone activity.
 
 0.909
EAR49998.1
COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
   
    0.869
EAR49436.1
Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators.
   
    0.868
EAR53008.1
COG2003 DNA repair proteins; Belongs to the UPF0758 family.
  
  
 0.831
EAR51560.1
Two-component sensor histidine kinase; COG2203 FOG: GAF domain.
  
  
 0.828
EAR51521.1
Putative Competence protein; COG0658 Predicted membrane metal-binding protein.
 
  
 0.817
fliP
Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
    0.801
fliP-2
Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
    0.801
Your Current Organism:
Oceanicola granulosus
NCBI taxonomy Id: 314256
Other names: O. granulosus HTCC2516, Oceanicola granulosus HTCC2516, Oceanicola granulosus KCTC 12143, Oceanicola granulosus str. HTCC2516, Oceanicola granulosus strain HTCC2516
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