Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ23823.1COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (645 aa)    
Predicted Functional Partners:
EAQ23825.1
Hypothetical protein; COG2207 AraC-type DNA-binding domain-containing proteins.
 
  
  0.840
EAQ23824.1
Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
 
    0.830
EAQ23096.1
COG0076 Glutamate decarboxylase and related PLP-dependent proteins.
   
 0.812
EAQ23495.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
 0.805
EAQ27140.1
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
  
 
 0.791
EAQ23975.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.781
EAQ25686.1
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
  
 0.779
EAQ25651.1
COG1145 Ferredoxin.
   
 0.725
EAQ26851.1
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.718
EAQ26854.1
Probable carboxylase; COG5016 Pyruvate/oxaloacetate carboxyltransferase.
    
 0.718
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
Server load: low (18%) [HD]