Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ24851.1Transcriptional regulator, gntR family protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (401 aa)    
Predicted Functional Partners:
EAQ24514.1
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
   
 
  0.702
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.682
EAQ24414.1
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
    
  0.606
EAQ25686.1
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
     
 0.530
EAQ26634.1
Putative aminomethyltransferase protein; Belongs to the GcvT family.
   
 
  0.525
EAQ25663.1
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
    
  0.513
EAQ23656.1
Threonine aldolase, low-specificity; COG3616 Predicted amino acid aldolase or racemase.
   
 
  0.509
EAQ24375.1
Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase.
     
  0.503
EAQ24524.1
COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family.
     
  0.503
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
  0.503
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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