Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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thiCThiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (600 aa)    
Predicted Functional Partners:
EAQ24437.1
COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.992
EAQ24433.1
Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase.
 
 
 0.945
EAQ24435.1
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
  
  
 0.942
EAQ26724.1
Thiamine-phosphate pyrophosphorylase, putative; COG0352 Thiamine monophosphate synthase.
  
 
 0.914
EAQ27324.1
Hypothetical protein; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.
  
  
 0.885
EAQ26336.1
Molybdopterin biosynthesis protein MoeB, putative; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
 
  
 0.790
EAQ24432.1
Thiamine biosynthesis protein ThiF; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
 
  
 0.752
EAQ24430.1
TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
  
 
 0.750
purM
COG0150 Phosphoribosylaminoimidazole (AIR) synthetase.
     
 0.730
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
     
  0.717
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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