Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ23098.1Putative transcriptional regulator; COG3710 DNA-binding winged-HTH domains. (515 aa)    
Predicted Functional Partners:
EAQ24428.1
COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
 
  
0.891
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.873
EAQ25094.1
COG1694 Predicted pyrophosphatase.
  
 
  0.868
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.867
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.862
EAQ25288.1
guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase, putative; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.861
EAQ23733.1
Transcriptional regulatory protein-like; COG2771 DNA-binding HTH domain-containing proteins.
 
 
0.788
EAQ23105.1
Hypothetical protein; COG3710 DNA-binding winged-HTH domains.
 
 
0.785
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
  0.755
EAQ24859.1
COG0457 FOG: TPR repeat.
  
 
 0.750
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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