Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ23344.1COG0462 Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (315 aa)    
Predicted Functional Partners:
EAQ23975.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.995
EAQ23345.1
COG0213 Thymidine phosphorylase.
 
  
 0.970
EAQ23346.1
Metallo-beta-lactamase family protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.
 
     0.917
EAQ23347.1
Hypothetical protein; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
     0.901
EAQ25474.1
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
    
 0.871
EAQ25767.1
Probable phosphoprotein phosphatase; COG0631 Serine/threonine protein phosphatase.
    
 0.848
EAQ25475.1
Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
 0.838
EAQ23974.1
Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.838
EAQ23342.1
Hypothetical protein.
 
     0.836
EAQ23359.1
COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase.
 
 
 0.823
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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