Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ25860.1Transcriptional regulator, GntR family protein; COG2188 Transcriptional regulators. (262 aa)    
Predicted Functional Partners:
EAQ25859.1
Possible phosphonate ABC transporter, permease component; COG3454 Metal-dependent hydrolase involved in phosphonate metabolism.
 
  
 0.870
EAQ25858.1
Phosphonates-binding protein; COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component.
 
  
 0.681
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.656
EAQ24044.1
Transcriptional regulator, GntR family protein; COG2188 Transcriptional regulators.
  
   
 0.653
EAQ25275.1
Alkylphosphonate utilization protein PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
 
  
 0.619
EAQ25273.1
Alkylphosphonate utilization protein PhnI; COG3626 Uncharacterized enzyme of phosphonate metabolism.
 
  
 0.606
EAQ25271.1
Alkylphosphonate utilization protein PhnG; COG3624 Uncharacterized enzyme of phosphonate metabolism.
 
  
 0.600
EAQ25856.1
COG3639 ABC-type phosphate/phosphonate transport system, permease component.
 
  
 0.585
EAQ25272.1
Alkylphosphonate utilization protein PhnH; COG3625 Uncharacterized enzyme of phosphonate metabolism.
 
  
 0.577
EAQ25281.1
Alkylphosphonate utilization protein PhnM; COG3454 Metal-dependent hydrolase involved in phosphonate metabolism.
 
  
 0.554
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
Server load: medium (42%) [HD]