| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ25429.1 | EAQ25487.1 | ROS217_06715 | ROS217_07005 | COG0167 Dihydroorotate dehydrogenase. | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.744 |
| EAQ25429.1 | dapE | ROS217_06715 | ROS217_04760 | COG0167 Dihydroorotate dehydrogenase. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.744 |
| EAQ25429.1 | glmS | ROS217_06715 | ROS217_08539 | COG0167 Dihydroorotate dehydrogenase. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.487 |
| EAQ25484.1 | EAQ25486.1 | ROS217_06990 | ROS217_07000 | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Putative oxidoreductase; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | 0.694 |
| EAQ25484.1 | EAQ25487.1 | ROS217_06990 | ROS217_07005 | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.710 |
| EAQ25486.1 | EAQ25484.1 | ROS217_07000 | ROS217_06990 | Putative oxidoreductase; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.694 |
| EAQ25486.1 | EAQ25487.1 | ROS217_07000 | ROS217_07005 | Putative oxidoreductase; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.773 |
| EAQ25487.1 | EAQ25429.1 | ROS217_07005 | ROS217_06715 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG0167 Dihydroorotate dehydrogenase. | 0.744 |
| EAQ25487.1 | EAQ25484.1 | ROS217_07005 | ROS217_06990 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.710 |
| EAQ25487.1 | EAQ25486.1 | ROS217_07005 | ROS217_07000 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Putative oxidoreductase; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | 0.773 |
| EAQ25487.1 | argB | ROS217_07005 | ROS217_12706 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.771 |
| EAQ25487.1 | argC | ROS217_07005 | ROS217_21462 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.809 |
| EAQ25487.1 | argD | ROS217_07005 | ROS217_21302 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.874 |
| EAQ25487.1 | argG | ROS217_07005 | ROS217_09772 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.891 |
| EAQ25487.1 | dapE | ROS217_07005 | ROS217_04760 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.861 |
| EAQ25487.1 | dapF | ROS217_07005 | ROS217_13746 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.861 |
| EAQ25487.1 | glmS | ROS217_07005 | ROS217_08539 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.755 |
| argB | EAQ25487.1 | ROS217_12706 | ROS217_07005 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.771 |
| argB | argC | ROS217_12706 | ROS217_21462 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
| argB | argD | ROS217_12706 | ROS217_21302 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.989 |