Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ25626.1Ketopantoate reductase ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (301 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
   
 0.887
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.859
EAQ25916.1
COG0413 Ketopantoate hydroxymethyltransferase.
   
 0.810
EAQ25623.1
COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
       0.773
EAQ25624.1
Transcription regulator; COG0251 Putative translation initiation inhibitor, yjgF family.
       0.773
EAQ25625.1
Phenazine biosynthesis family protein; COG0384 Predicted epimerase, PhzC/PhzF homolog.
       0.773
EAQ24564.1
COG3145 Alkylated DNA repair protein.
   
    0.729
EAQ23946.1
Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
   
    0.652
EAQ25627.1
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
    0.596
EAQ26213.1
Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases.
 
    0.546
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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