Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ25630.1COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (292 aa)    
Predicted Functional Partners:
EAQ24414.1
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
    
  0.607
EAQ26407.1
Hydroxypyruvate isomerase, putative; COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.607
EAQ26851.1
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
  0.607
EAQ26854.1
Probable carboxylase; COG5016 Pyruvate/oxaloacetate carboxyltransferase.
     
  0.607
EAQ27458.1
Phosphate acetyltransferase; COG2030 Acyl dehydratase.
     
 0.566
EAQ26404.1
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
  
 
0.534
EAQ25629.1
Hypothetical protein; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
       0.513
EAQ24585.1
HpcH/HpaI aldolase family protein; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
  0.504
EAQ25628.1
Putative 3-hydroxybutyryl-CoA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
  0.501
EAQ25104.1
6-phosphogluconate dehydrogenase domain protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
  
 
0.498
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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