Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ23555.1COG0789 Predicted transcriptional regulators. (128 aa)    
Predicted Functional Partners:
EAQ23554.1
Copper-translocating P-type ATPase; COG2217 Cation transport ATPase.
  
  
 0.828
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
  0.745
EAQ24514.1
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
     
 0.726
EAQ27445.1
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
   
 0.670
EAQ24538.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
     
  0.632
EAQ26284.1
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
     
  0.632
EAQ26608.1
Sensory box histidine kinase/response regulator; COG5002 Signal transduction histidine kinase.
   
 0.593
EAQ23495.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
    
  0.587
EAQ24871.1
Two-component sensor; COG0642 Signal transduction histidine kinase.
   
 0.575
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.553
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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