STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ23569.1Modification methylase (Cytosine-specific methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (511 aa)    
Predicted Functional Partners:
EAQ23563.1
Endonuclease.
  
 0.837
EAQ23570.1
DNA mismatch endonuclease Vsr, putative; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.833
EAQ23562.1
Hypothetical protein; COG0323 DNA mismatch repair enzyme (predicted ATPase).
 
  
 0.783
EAQ23564.1
Hypothetical protein.
 
     0.776
EAQ23565.1
Hypothetical protein.
 
   
 0.753
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.736
EAQ23561.1
RNA polymerase sigma subunit; COG0666 FOG: Ankyrin repeat; Belongs to the sigma-70 factor family.
 
   
 0.735
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.690
EAQ24726.1
Autoinducer synthesis protein RhlL; COG3916 N-acyl-L-homoserine lactone synthetase; Belongs to the autoinducer synthase family.
     
 0.659
EAQ26796.1
XorII very-short-patch-repair endonuclease; COG3727 DNA G:T-mismatch repair endonuclease.
 
   
 0.571
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.