Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ23590.1Hypothetical protein; COG1396 Predicted transcriptional regulators. (133 aa)    
Predicted Functional Partners:
EAQ23589.1
Hypothetical protein.
       0.773
EAQ23108.1
Hypothetical protein.
  
     0.602
EAQ23937.1
Hypothetical protein; COG5519 Superfamily II helicase and inactivated derivatives.
  
     0.560
EAQ25880.1
Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.523
EAQ23495.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
     
  0.523
nadE
NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
  0.523
EAQ25540.1
Hypothetical protein.
  
     0.508
EAQ24435.1
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
     
  0.472
EAQ24176.1
Hypothetical protein.
  
     0.464
EAQ25596.1
Tetratricopeptide; COG0457 FOG: TPR repeat.
     
  0.403
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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