Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ttcAHypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (289 aa)    
Predicted Functional Partners:
EAQ24514.1
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
  0.840
EAQ26952.1
Putative aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
    
 0.821
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.816
EAQ24311.1
Diguanylate cyclase, putative; COG2199 FOG: GGDEF domain.
       0.790
EAQ26558.1
Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation.
     
 0.737
EAQ24348.1
COG0314 Molybdopterin converting factor, large subunit.
     
 0.733
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.714
EAQ26754.1
Fe-S metabolism associated family protein; COG2166 SufE protein probably involved in Fe-S center assembly.
    
 0.713
EAQ25313.1
Cytochrome c oxidase polypeptide II precursor (Cytochrome AA3 subunit 2); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
     
  0.708
EAQ26517.1
Cytochrome c oxidase, aa3-type, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
     
  0.708
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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