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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
EAQ24437.1COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (264 aa)    
Predicted Functional Partners:
EAQ24430.1
TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
 0.999
EAQ24433.1
Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase.
 
 0.999
thiC
Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.992
EAQ24435.1
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
 
 
 0.992
EAQ26724.1
Thiamine-phosphate pyrophosphorylase, putative; COG0352 Thiamine monophosphate synthase.
  
 
 0.982
EAQ27326.1
Pet18 protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family.
 
 
 0.961
EAQ24432.1
Thiamine biosynthesis protein ThiF; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
 
  
 0.954
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
     0.920
EAQ24436.1
COG0665 Glycine/D-amino acid oxidases (deaminating).
 
  
 0.907
EAQ24431.1
ABC transporter, periplasmic substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.
 
  
  0.906
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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