Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ24129.1Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. (122 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
  0.751
EAQ24514.1
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
     
 0.726
EAQ24127.1
COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.
  
    0.708
EAQ24126.1
DNA-damage-inducible protein F; COG0534 Na+-driven multidrug efflux pump.
       0.701
EAQ24130.1
Transcriptional regulator, merR family protein; COG0789 Predicted transcriptional regulators.
 
    
0.687
EAQ27445.1
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
   
 0.670
EAQ24128.1
Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.
  
    0.635
EAQ24538.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
     
  0.632
EAQ26284.1
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
     
  0.632
EAQ26608.1
Sensory box histidine kinase/response regulator; COG5002 Signal transduction histidine kinase.
   
 0.593
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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