Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ25980.1COG1802 Transcriptional regulators. (218 aa)    
Predicted Functional Partners:
EAQ25981.1
Hypothetical protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
 
     0.848
EAQ25982.1
Hypothetical protein; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.817
EAQ25984.1
Hypothetical protein.
 
    0.735
EAQ25983.1
Hypothetical protein; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
 
    0.679
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.625
EAQ25978.1
SsrA-binding protein.
       0.601
EAQ25985.1
malonyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
     0.536
EAQ22960.1
Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators.
  
  
 0.523
EAQ25976.1
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
       0.450
EAQ25977.1
Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase.
       0.450
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.