Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ26214.1COG0169 Shikimate 5-dehydrogenase. (287 aa)    
Predicted Functional Partners:
EAQ26213.1
Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases.
 
 
 0.988
EAQ26216.1
Hypothetical protein.
 
     0.929
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.852
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 0.830
EAQ26215.1
COG3333 Uncharacterized protein conserved in bacteria.
 
     0.824
EAQ26211.1
COG3485 Protocatechuate 3,4-dioxygenase beta subunit.
 
   
 0.812
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 
 0.811
EAQ26208.1
PcaL, 3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.810
EAQ26210.1
COG3485 Protocatechuate 3,4-dioxygenase beta subunit.
 
   
 0.810
EAQ26212.1
4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
     0.810
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.