Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EAQ26455.1BFD-like (2Fe-2S)-binding region protein; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (810 aa)    
Predicted Functional Partners:
EAQ26456.1
Hypothetical protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
 
 
 0.997
EAQ26457.1
Putative nitrate reductase, large subunit protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
 0.995
EAQ26454.1
COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.
 
  
 0.949
EAQ26453.1
Putative nitrate transporter; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.
 
  
 0.939
EAQ26452.1
COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.
 
 
 0.922
EAQ26459.1
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
  
 0.915
EAQ23340.1
COG2717 Predicted membrane protein.
  
 
 0.905
EAQ26451.1
Nitrate transporter component, nrtA; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.
 
 
 0.892
EAQ26450.1
COG3707 Response regulator with putative antiterminator output domain.
 
  
 0.880
EAQ26458.1
Hypothetical protein; COG0547 Anthranilate phosphoribosyltransferase.
 
     0.854
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
Server load: medium (52%) [HD]