Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ24978.1Peptidase, M23/M37 family protein; COG0739 Membrane proteins related to metalloendopeptidases. (416 aa)    
Predicted Functional Partners:
EAQ24977.1
COG1664 Integral membrane protein CcmA involved in cell shape determination.
 
   
 0.888
EAQ26662.1
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
  
   
 0.698
EAQ25249.1
Penicillin-binding protein, 1A family protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.672
EAQ24981.1
COG2911 Uncharacterized protein conserved in bacteria.
 
     0.581
EAQ24980.1
AhpC/TSA family protein; COG1225 Peroxiredoxin.
  
  
 0.577
EAQ27400.1
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
   
 0.575
EAQ25294.1
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.561
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.552
mltG
Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.543
EAQ24979.1
COG2833 Uncharacterized protein conserved in bacteria.
       0.536
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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