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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (488 aa)    
Predicted Functional Partners:
EAQ26197.1
Precorrin-3B C17-methyltransferase region; COG2073 Cobalamin biosynthesis protein CbiG.
  
 0.996
EAQ26342.1
COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.
 
 0.996
EAQ26194.1
precorrin-8X methylmutase; COG2082 Precorrin isomerase.
  
 0.992
EAQ22957.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.983
EAQ26198.1
COG2875 Precorrin-4 methylase.
 
  
 0.982
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.982
EAQ26196.1
Cobalamin biosynthesis precorrin-2 methyltransferase; COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.979
EAQ27258.1
Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
 
 0.977
EAQ27220.1
COG2099 Precorrin-6x reductase.
 
  
 0.975
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.969
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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