Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ27324.1Hypothetical protein; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit. (200 aa)    
Predicted Functional Partners:
EAQ23392.1
Response regulator; COG0784 FOG: CheY-like receiver.
 
    0.987
EAQ26253.1
Anti-sigma B factor, putative; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
    0.982
EAQ26254.1
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
    0.980
EAQ27323.1
Diguanylate cyclase, putative; COG2199 FOG: GGDEF domain.
 
  
 0.980
EAQ24202.1
COG1815 Flagellar basal body protein.
   
    0.952
EAQ23391.1
COG2198 FOG: HPt domain.
 
    0.903
thiC
Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.885
EAQ24435.1
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
  
 
  0.884
EAQ24946.1
COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
   
    0.866
EAQ24433.1
Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase.
  
  
 0.820
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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