Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (708 aa)    
Predicted Functional Partners:
EAQ23495.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
 
 
 0.981
EAQ27458.1
Phosphate acetyltransferase; COG2030 Acyl dehydratase.
  
 
 0.971
EAQ24375.1
Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase.
  
 
 0.952
EAQ27126.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
   
 0.942
EAQ24376.1
Glycolate oxidase, GlcE subunit; COG0277 FAD/FMN-containing dehydrogenases.
  
 
 0.930
ackA
Putative acetate kinase: ACKA OR; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.927
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.923
EAQ27394.1
Putative glcG protein; COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol.
  
  
 0.902
EAQ23836.1
COG0372 Citrate synthase.
   
 0.891
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.890
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
Server load: low (22%) [HD]