Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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cobSPutative Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (187 aa)    
Predicted Functional Partners:
EAQ26197.1
Precorrin-3B C17-methyltransferase region; COG2073 Cobalamin biosynthesis protein CbiG.
 
  
 0.960
cobT
Nicotinate-nucleotide-- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.959
EAQ26342.1
COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.
 
 
 0.945
EAQ22957.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.926
EAQ26343.1
Phosphoglycerate mutase family protein; COG0406 Fructose-2,6-bisphosphatase.
 
 
 0.893
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.877
EAQ22815.1
COG0368 Cobalamin-5-phosphate synthase.
 
     0.820
EAQ26198.1
COG2875 Precorrin-4 methylase.
 
 
 0.807
EAQ27220.1
COG2099 Precorrin-6x reductase.
 
  
 0.776
EAQ26690.1
Hypothetical protein.
   
    0.768
Your Current Organism:
Roseovarius sp. 217
NCBI taxonomy Id: 314264
Other names: R. sp. 217
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