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hpbD protein (Pelagibaca bermudensis) - STRING interaction network
"hpbD" - (4R)-4-hydroxyproline betaine 2-epimerase in Pelagibaca bermudensis
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
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hpbD(4R)-4-hydroxyproline betaine 2-epimerase; Catalyzes the 2-epimerization of trans-4-hydroxy-L- proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp- B). Is involved in a catabolic pathway that degrades tHyp-B to alpha-ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine (367 aa)    
Predicted Functional Partners:
R2601_12528
Mandelate racemase/muconate lactonizing enzyme family protein (329 aa)
 
   
    0.741
R2601_01633
Trimethylamine methyltransferase MttB-like protein (490 aa)
 
          0.738
R2601_02998
Isomerase/lactonizing enzyme (382 aa)
 
   
    0.681
R2601_01623
Putative aromatic-ring hydroxylating dioxygenase, alpha-subunit (418 aa)
 
          0.574
R2601_10859
Twin-arginine translocation pathway signal (252 aa)
   
   
    0.481
R2601_01628
Possible dioxygenase reductase subunit (362 aa)
              0.470
R2601_11389
Rieske 2Fe-2S domain protein (374 aa)
   
          0.468
R2601_13124
Protocatechuate 3,4-dioxygenase alpha subunit (230 aa)
   
   
    0.455
R2601_13129
Protocatechuate 3,4-dioxygenase beta subunit (241 aa)
   
   
    0.438
R2601_12825
Putative cycloisomerase (375 aa)
 
   
 
0.407
Your Current Organism:
Pelagibaca bermudensis
NCBI taxonomy Id: 314265
Other names: P. bermudensis HTCC2601, Pelagibaca, Pelagibaca Cho and Giovannoni 2006, Pelagibaca bermudensis, Pelagibaca bermudensis Cho and Giovannoni 2006, Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601
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