node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAU43512.1 | EAU46157.1 | R2601_13129 | R2601_01628 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.453 |
EAU43512.1 | EAU48411.1 | R2601_13129 | R2601_02523 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG0412 Dienelactone hydrolase and related enzymes. | 0.430 |
EAU43512.1 | hpbD | R2601_13129 | R2601_01638 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | Mandelate racemase/muconate lactonizing enzyme; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine. | 0.499 |
EAU44812.1 | EAU45441.1 | R2601_22252 | R2601_00575 | COG2721 Altronate dehydratase. | Putative aldolase; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. | 0.703 |
EAU44812.1 | EAU48506.1 | R2601_22252 | R2601_02998 | COG2721 Altronate dehydratase. | Isomerase/lactonizing enzyme; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.733 |
EAU44812.1 | hpbD | R2601_22252 | R2601_01638 | COG2721 Altronate dehydratase. | Mandelate racemase/muconate lactonizing enzyme; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine. | 0.476 |
EAU45441.1 | EAU44812.1 | R2601_00575 | R2601_22252 | Putative aldolase; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. | COG2721 Altronate dehydratase. | 0.703 |
EAU45441.1 | EAU48506.1 | R2601_00575 | R2601_02998 | Putative aldolase; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. | Isomerase/lactonizing enzyme; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.621 |
EAU45441.1 | hpbD | R2601_00575 | R2601_01638 | Putative aldolase; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. | Mandelate racemase/muconate lactonizing enzyme; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine. | 0.484 |
EAU46156.1 | EAU46157.1 | R2601_01623 | R2601_01628 | Putative aromatic-ring hydroxylating dioxygenase, alpha-subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.991 |
EAU46156.1 | EAU46158.1 | R2601_01623 | R2601_01633 | Putative aromatic-ring hydroxylating dioxygenase, alpha-subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.518 |
EAU46156.1 | hpbD | R2601_01623 | R2601_01638 | Putative aromatic-ring hydroxylating dioxygenase, alpha-subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. | Mandelate racemase/muconate lactonizing enzyme; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine. | 0.518 |
EAU46157.1 | EAU43512.1 | R2601_01628 | R2601_13129 | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.453 |
EAU46157.1 | EAU46156.1 | R2601_01628 | R2601_01623 | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Putative aromatic-ring hydroxylating dioxygenase, alpha-subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. | 0.991 |
EAU46157.1 | EAU46158.1 | R2601_01628 | R2601_01633 | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.518 |
EAU46157.1 | hpbD | R2601_01628 | R2601_01638 | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Mandelate racemase/muconate lactonizing enzyme; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine. | 0.799 |
EAU46158.1 | EAU46156.1 | R2601_01633 | R2601_01623 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Putative aromatic-ring hydroxylating dioxygenase, alpha-subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit. | 0.518 |
EAU46158.1 | EAU46157.1 | R2601_01633 | R2601_01628 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Possible dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.518 |
EAU46158.1 | hpbD | R2601_01633 | R2601_01638 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Mandelate racemase/muconate lactonizing enzyme; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. To a lesser extent, can also catalyze the racemization of L-proline betaine. | 0.672 |
EAU48411.1 | EAU43512.1 | R2601_02523 | R2601_13129 | COG0412 Dienelactone hydrolase and related enzymes. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.430 |