node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAU43573.1 | EAU44097.1 | R2601_24130 | R2601_12081 | COG1200 RecG-like helicase. | COG0514 Superfamily II DNA helicase. | 0.696 |
EAU43573.1 | EAU44635.1 | R2601_24130 | R2601_24245 | COG1200 RecG-like helicase. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.536 |
EAU43573.1 | EAU46384.1 | R2601_24130 | R2601_10022 | COG1200 RecG-like helicase. | single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease. | 0.766 |
EAU43573.1 | EAU47016.1 | R2601_24130 | R2601_17819 | COG1200 RecG-like helicase. | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.446 |
EAU43573.1 | EAU48168.1 | R2601_24130 | R2601_14420 | COG1200 RecG-like helicase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.518 |
EAU43573.1 | mfd | R2601_24130 | R2601_25451 | COG1200 RecG-like helicase. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.558 |
EAU43573.1 | polA | R2601_24130 | R2601_15447 | COG1200 RecG-like helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.784 |
EAU43573.1 | topA | R2601_24130 | R2601_17824 | COG1200 RecG-like helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.770 |
EAU44097.1 | EAU43573.1 | R2601_12081 | R2601_24130 | COG0514 Superfamily II DNA helicase. | COG1200 RecG-like helicase. | 0.696 |
EAU44097.1 | EAU44635.1 | R2601_12081 | R2601_24245 | COG0514 Superfamily II DNA helicase. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.426 |
EAU44097.1 | EAU46384.1 | R2601_12081 | R2601_10022 | COG0514 Superfamily II DNA helicase. | single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease. | 0.712 |
EAU44097.1 | EAU48168.1 | R2601_12081 | R2601_14420 | COG0514 Superfamily II DNA helicase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.959 |
EAU44097.1 | polA | R2601_12081 | R2601_15447 | COG0514 Superfamily II DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
EAU44097.1 | topA | R2601_12081 | R2601_17824 | COG0514 Superfamily II DNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.996 |
EAU44635.1 | EAU43573.1 | R2601_24245 | R2601_24130 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | COG1200 RecG-like helicase. | 0.536 |
EAU44635.1 | EAU44097.1 | R2601_24245 | R2601_12081 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | COG0514 Superfamily II DNA helicase. | 0.426 |
EAU44635.1 | EAU46384.1 | R2601_24245 | R2601_10022 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease. | 0.717 |
EAU44635.1 | EAU47016.1 | R2601_24245 | R2601_17819 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.468 |
EAU44635.1 | EAU48168.1 | R2601_24245 | R2601_14420 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.757 |
EAU44635.1 | mfd | R2601_24245 | R2601_25451 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.467 |