STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAU44531.1Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (352 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.995
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 
 0.995
EAU48069.1
Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
 0.983
carB-2
COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
 
 0.973
EAU45445.1
Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
 0.962
EAU44164.1
Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
 0.962
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.957
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 0.946
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.944
carA
COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.941
Your Current Organism:
Salipiger bermudensis
NCBI taxonomy Id: 314265
Other names: Pelagibaca bermudensis HTCC2601, Pelagibaca bermudensis str. HTCC2601, Pelagibaca bermudensis strain HTCC2601, Roseovarius sp. HTCC2601, S. bermudensis HTCC2601, Salipiger bermudensis HTCC2601
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