node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAU43507.1 | EAU43511.1 | R2601_13104 | R2601_13124 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.979 |
EAU43507.1 | EAU43512.1 | R2601_13104 | R2601_13129 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.981 |
EAU43507.1 | EAU43513.1 | R2601_13104 | R2601_13134 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.981 |
EAU43507.1 | purA | R2601_13104 | R2601_26736 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.958 |
EAU43507.1 | purC | R2601_13104 | R2601_24440 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.957 |
EAU43507.1 | purD | R2601_13104 | R2601_21021 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.954 |
EAU43507.1 | purE | R2601_13104 | R2601_12373 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.940 |
EAU43507.1 | purH | R2601_13104 | R2601_08606 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.955 |
EAU43507.1 | purN | R2601_13104 | R2601_23420 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.951 |
EAU43507.1 | purS | R2601_13104 | R2601_24445 | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.941 |
EAU43511.1 | EAU43507.1 | R2601_13124 | R2601_13104 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 0.979 |
EAU43511.1 | EAU43512.1 | R2601_13124 | R2601_13129 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.999 |
EAU43511.1 | EAU43513.1 | R2601_13124 | R2601_13134 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.983 |
EAU43512.1 | EAU43507.1 | R2601_13129 | R2601_13104 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 0.981 |
EAU43512.1 | EAU43511.1 | R2601_13129 | R2601_13124 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.999 |
EAU43512.1 | EAU43513.1 | R2601_13129 | R2601_13134 | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 0.984 |
EAU43513.1 | EAU43507.1 | R2601_13134 | R2601_13104 | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 0.981 |
EAU43513.1 | EAU43511.1 | R2601_13134 | R2601_13124 | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.983 |
EAU43513.1 | EAU43512.1 | R2601_13134 | R2601_13129 | 4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. | COG3485 Protocatechuate 3,4-dioxygenase beta subunit. | 0.984 |
purA | EAU43507.1 | R2601_26736 | R2601_13104 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 3-carboxy-cis,cis-muconate cycloisomerase; COG0015 Adenylosuccinate lyase. | 0.958 |