node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAU44072.1 | EAU44654.1 | R2601_08236 | R2601_24340 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | 0.786 |
EAU44072.1 | EAU44655.1 | R2601_08236 | R2601_24345 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | COG0795 Predicted permeases. | 0.694 |
EAU44072.1 | EAU46225.1 | R2601_08236 | R2601_25046 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.919 |
EAU44072.1 | EAU46452.1 | R2601_08236 | R2601_15512 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | ABC transporter, ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component. | 0.728 |
EAU44072.1 | lptD | R2601_08236 | R2601_24335 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 0.504 |
EAU44072.1 | lpxA | R2601_08236 | R2601_25056 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.989 |
EAU44072.1 | lpxD | R2601_08236 | R2601_24509 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.988 |
EAU44072.1 | lpxK | R2601_08236 | R2601_08661 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | Putative Tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.918 |
EAU44652.1 | EAU44654.1 | R2601_24330 | R2601_24340 | PPIC-type PPIASE domain; COG0760 Parvulin-like peptidyl-prolyl isomerase. | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | 0.882 |
EAU44652.1 | EAU44655.1 | R2601_24330 | R2601_24345 | PPIC-type PPIASE domain; COG0760 Parvulin-like peptidyl-prolyl isomerase. | COG0795 Predicted permeases. | 0.883 |
EAU44652.1 | lptD | R2601_24330 | R2601_24335 | PPIC-type PPIASE domain; COG0760 Parvulin-like peptidyl-prolyl isomerase. | Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 0.971 |
EAU44652.1 | pdxA | R2601_24330 | R2601_24325 | PPIC-type PPIASE domain; COG0760 Parvulin-like peptidyl-prolyl isomerase. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.805 |
EAU44654.1 | EAU44072.1 | R2601_24340 | R2601_08236 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. | 0.786 |
EAU44654.1 | EAU44652.1 | R2601_24340 | R2601_24330 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | PPIC-type PPIASE domain; COG0760 Parvulin-like peptidyl-prolyl isomerase. | 0.882 |
EAU44654.1 | EAU44655.1 | R2601_24340 | R2601_24345 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | COG0795 Predicted permeases. | 0.999 |
EAU44654.1 | EAU46225.1 | R2601_24340 | R2601_25046 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.791 |
EAU44654.1 | EAU46452.1 | R2601_24340 | R2601_15512 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | ABC transporter, ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component. | 0.999 |
EAU44654.1 | lptD | R2601_24340 | R2601_24335 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 0.981 |
EAU44654.1 | lpxA | R2601_24340 | R2601_25056 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.785 |
EAU44654.1 | lpxD | R2601_24340 | R2601_24509 | Permease, YjgP/YjgQ family protein; COG0795 Predicted permeases. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.776 |