STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAT07517.1Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (313 aa)    
Predicted Functional Partners:
EAT07516.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 0.998
EAT08701.1
Siroheme synthase; COG0007 Uroporphyrinogen-III methylase.
 
 0.998
EAT07340.1
Porphobilinogen synthase; COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.997
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 0.990
EAT10593.1
uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase.
 
 0.981
EAT07269.1
uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase.
 
 0.977
EAT07653.1
COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
 
 
 0.961
EAT07515.1
Hypothetical protein.
    
  0.945
tsaD
Metal-dependent protease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
  
 0.731
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
   
    0.693
Your Current Organism:
Sphingomonas sp. SKA58
NCBI taxonomy Id: 314266
Other names: S. sp. SKA58
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