node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAT07370.1 | dapE | SKA58_13982 | SKA58_13977 | Hypothetical protein; COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.746 |
EAT09639.1 | EAT09762.1 | SKA58_15122 | SKA58_15737 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.446 |
EAT09639.1 | argC | SKA58_15122 | SKA58_07870 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.625 |
EAT09639.1 | argD | SKA58_15122 | SKA58_05340 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.506 |
EAT09639.1 | argG | SKA58_15122 | SKA58_06090 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.459 |
EAT09639.1 | dapB | SKA58_15122 | SKA58_08679 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.677 |
EAT09639.1 | dapE | SKA58_15122 | SKA58_13977 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.630 |
EAT09639.1 | dapF | SKA58_15122 | SKA58_05740 | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.689 |
EAT09762.1 | EAT09639.1 | SKA58_15737 | SKA58_15122 | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aminotransferase, class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.446 |
EAT09762.1 | EAT09787.1 | SKA58_15737 | SKA58_15862 | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.530 |
EAT09762.1 | EAT09856.1 | SKA58_15737 | SKA58_05345 | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.635 |
EAT09762.1 | argC | SKA58_15737 | SKA58_07870 | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.625 |
EAT09762.1 | argD | SKA58_15737 | SKA58_05340 | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.585 |
EAT09762.1 | dapE | SKA58_15737 | SKA58_13977 | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.778 |
EAT09787.1 | EAT09762.1 | SKA58_15862 | SKA58_15737 | Hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.530 |
EAT09787.1 | dapE | SKA58_15862 | SKA58_13977 | Hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.675 |
EAT09856.1 | EAT09762.1 | SKA58_05345 | SKA58_15737 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 4-aminobutyrate aminotransferase and related aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.635 |
EAT09856.1 | argC | SKA58_05345 | SKA58_07870 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.976 |
EAT09856.1 | argD | SKA58_05345 | SKA58_05340 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.995 |
EAT09856.1 | argG | SKA58_05345 | SKA58_06090 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.997 |