node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAT06838.1 | EAT08009.1 | SKA58_14287 | SKA58_08594 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | 0.881 |
EAT06838.1 | EAT08400.1 | SKA58_14287 | SKA58_13728 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | ATP-dependent helicase HrpB; COG1643 HrpA-like helicases. | 0.643 |
EAT06838.1 | EAT09422.1 | SKA58_14287 | SKA58_03880 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.926 |
EAT06838.1 | EAT09856.1 | SKA58_14287 | SKA58_05345 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.723 |
EAT06838.1 | carA | SKA58_14287 | SKA58_08234 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.958 |
EAT06838.1 | carB | SKA58_14287 | SKA58_08249 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.958 |
EAT06838.1 | guaB | SKA58_14287 | SKA58_12682 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.651 |
EAT06838.1 | pyrB | SKA58_14287 | SKA58_14292 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
EAT06838.1 | pyrD | SKA58_14287 | SKA58_17962 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.988 |
EAT06838.1 | pyrE | SKA58_14287 | SKA58_15817 | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.889 |
EAT08009.1 | EAT06838.1 | SKA58_08594 | SKA58_14287 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | 0.881 |
EAT08009.1 | EAT09422.1 | SKA58_08594 | SKA58_03880 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.879 |
EAT08009.1 | carA | SKA58_08594 | SKA58_08234 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.948 |
EAT08009.1 | carB | SKA58_08594 | SKA58_08249 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.959 |
EAT08009.1 | guaB | SKA58_08594 | SKA58_12682 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.559 |
EAT08009.1 | pyrB | SKA58_08594 | SKA58_14292 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.977 |
EAT08009.1 | pyrD | SKA58_08594 | SKA58_17962 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.982 |
EAT08009.1 | pyrE | SKA58_08594 | SKA58_15817 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
EAT08400.1 | EAT06838.1 | SKA58_13728 | SKA58_14287 | ATP-dependent helicase HrpB; COG1643 HrpA-like helicases. | Dihydroorotase; COG0505 Carbamoylphosphate synthase small subunit. | 0.643 |
EAT08400.1 | EAT09422.1 | SKA58_13728 | SKA58_03880 | ATP-dependent helicase HrpB; COG1643 HrpA-like helicases. | COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.643 |