STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ40598.1Conserved hypothetical protein. (69 aa)    
Predicted Functional Partners:
EDZ43276.1
ATP phosphoribosyltransferase regulatory subunit; [J] COG0124 Histidyl-tRNA synthetase.
 
     0.764
EDZ41436.1
Conserved hypothetical protein.
  
     0.731
EDZ42365.1
Conserved hypothetical protein.
  
     0.722
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
       0.709
hisS
histidyl-tRNA synthetase; [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis.
       0.709
EDZ42825.1
[S] COG1426 Uncharacterized protein conserved in bacteria.
  
     0.709
EDZ44504.1
Conserved hypothetical protein.
  
     0.696
EDZ43899.1
Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
  
     0.691
EDZ42715.1
Conserved hypothetical protein.
  
     0.661
EDZ41832.1
Conserved hypothetical protein.
  
     0.646
Your Current Organism:
Rhodobacteraceae bacterium HTCC2083
NCBI taxonomy Id: 314270
Other names: R. bacterium HTCC2083, Rhodobacterales bacterium HTCC2083
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.