STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaRHomoprotocatechuate degradation operon regulator, HpaR; [K] COG1846 Transcriptional regulators. (163 aa)    
Predicted Functional Partners:
hpcD
[E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase.
 
   
 0.896
hpaD
3,4-dihydroxyphenylacetate 2,3-dioxygenase; [E] COG0346 Lactoylglutathione lyase and related lyases.
 
  
  0.860
hpaH
2-oxo-hepta-3-ene-1,7-dioic acid hydratase; [Q] COG3971 2-keto-4-pentenoate hydratase.
 
     0.823
hpaE
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; Belongs to the aldehyde dehydrogenase family.
 
  
  0.794
EDZ41872.1
5-carboxymethyl-2-hydroxymuconate delta-isomerase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
     0.728
hpaI
[G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
   
 0.661
EDZ43783.1
Tyrosine decarboxylase 1; [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins.
 
     0.586
RB2083_33
N-6 Adenine-specific DNA methylase; [S] COG5441 Uncharacterized conserved protein.
  
     0.576
RB2083_16
Conserved hypothetical protein.
  
     0.571
EDZ44055.1
Cytochrome c, class I; [C] COG3474 Cytochrome c2.
   
 
  0.570
Your Current Organism:
Rhodobacteraceae bacterium HTCC2083
NCBI taxonomy Id: 314270
Other names: R. bacterium HTCC2083, Rhodobacterales bacterium HTCC2083
Server load: low (18%) [HD]