node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDZ41797.1 | EDZ42764.1 | RB2083_1312 | RB2083_2279 | Conserved hypothetical protein. | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.775 |
EDZ41797.1 | EDZ42825.1 | RB2083_1312 | RB2083_2340 | Conserved hypothetical protein. | [S] COG1426 Uncharacterized protein conserved in bacteria. | 0.765 |
EDZ42764.1 | EDZ41797.1 | RB2083_2279 | RB2083_1312 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Conserved hypothetical protein. | 0.775 |
EDZ42764.1 | EDZ42825.1 | RB2083_2279 | RB2083_2340 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | [S] COG1426 Uncharacterized protein conserved in bacteria. | 0.786 |
EDZ42764.1 | EDZ43597.1 | RB2083_2279 | RB2083_3112 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | 0.793 |
EDZ42764.1 | addA | RB2083_2279 | RB2083_3898 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Double-strand break repair helicase AddA; [L] COG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. | 0.983 |
EDZ42764.1 | dnaN | RB2083_2279 | RB2083_2374 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.972 |
EDZ42764.1 | helD | RB2083_2279 | RB2083_3057 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Helicase IV; [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). | 0.780 |
EDZ42764.1 | raiI | RB2083_2279 | RB2083_730 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Autoinducer synthesis protein; [TQ] COG3916 N-acyl-L-homoserine lactone synthetase. | 0.803 |
EDZ42764.1 | recA | RB2083_2279 | RB2083_1689 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.762 |
EDZ42764.1 | recQ | RB2083_2279 | RB2083_2019 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | [LKJ] COG0513 Superfamily II DNA and RNA helicases. | 0.911 |
EDZ42764.1 | topA | RB2083_2279 | RB2083_2333 | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.756 |
EDZ42825.1 | EDZ41797.1 | RB2083_2340 | RB2083_1312 | [S] COG1426 Uncharacterized protein conserved in bacteria. | Conserved hypothetical protein. | 0.765 |
EDZ42825.1 | EDZ42764.1 | RB2083_2340 | RB2083_2279 | [S] COG1426 Uncharacterized protein conserved in bacteria. | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.786 |
EDZ43597.1 | EDZ42764.1 | RB2083_3112 | RB2083_2279 | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | ATPase; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. | 0.793 |
EDZ43597.1 | addA | RB2083_3112 | RB2083_3898 | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Double-strand break repair helicase AddA; [L] COG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. | 0.645 |
EDZ43597.1 | dnaN | RB2083_3112 | RB2083_2374 | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.933 |
EDZ43597.1 | recA | RB2083_3112 | RB2083_1689 | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.951 |
EDZ43597.1 | recQ | RB2083_3112 | RB2083_2019 | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | [LKJ] COG0513 Superfamily II DNA and RNA helicases. | 0.971 |
EDZ43597.1 | topA | RB2083_3112 | RB2083_2333 | UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.863 |