STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ43032.1[R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. (555 aa)    
Predicted Functional Partners:
EDZ44320.1
[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
      0.923
ispB
[H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.863
ispA
Geranyltranstransferase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.863
coaX
Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.852
nuoN
NADH-quinone oxidoreductase chain n; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
  
    0.771
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.717
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
      0.659
EDZ44613.1
Proton-translocating NADH-quinone oxidoreductase, chain L subfamily; [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.
  
    0.641
nuoK
NADH-quinone oxidoreductase chain k; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.
       0.638
nuoM
[C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M).
       0.638
Your Current Organism:
Rhodobacteraceae bacterium HTCC2083
NCBI taxonomy Id: 314270
Other names: R. bacterium HTCC2083, Rhodobacterales bacterium HTCC2083
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.